In order to effectively improve the structural damage and environmental pollution caused by bamboo and wood raft cultivation equipment in Beibu Gulf of Guangxi in the process of long-term use, and improve its ability to withstand wind and waves, the HDPE raft culture equipment was selected as the research object, taking the common 15 m long and 12 m wide single raft in Beibu Gulf of Guangxi as an example. AQWA software was used to establish a hydrodynamic analysis model, and based on frequency domain analysis and time domain analysis methods, mooring length and mooring Angle were taken as response indexes to carry out research on the hydrodynamic characteristics and motion response of raft farming equipment, and obtain the motion response and mooring tension variation rules of various degrees of freedom of raft farming equipment. The results show: Under the condition of level 7th high wind and waves, the motion response and mooring cable tension of raft culture equipment change significantly under different mooring lengths and angles. When the ratio of mooring cable length to water depth l/d =1.08 and the Angle of mooring cable is less than 30°, the motion response and mooring cable tension of raft culture equipment are smaller. The optimum mooring form is determined under this condition. Conclusion: Through theoretical and numerical simulation analysis, parameter comparison and early warning are provided for the structural state and safety of aquaculture equipment under different sea conditions, and theoretical reference is also provided for the better application of HDPE materials to raft aquaculture equipment.