In order to address the serious environmental pollution in the traditional aquaculture of crayfish, a LoRa-based monitoring system for crayfish ecological aquaculture that combines ecological control with intelligent control is designed. The system adopts circulating water transfer mode, and based on the principle of complementary symbiosis between cultured organisms, a mixed ecological aquaculture model of “rice, grass and shrimp” is designed. The water quality data information is collected by LoRa technology, the dissolved oxygen concentration is intelligently processed according to the fuzzy control algorithm, and the control command is issued to the lower computer. In addition, VPN is built through 4G router and cloud server to realize remote control of the system. The result shows that LoRa technology overcomes the problems of low power consumption and short distance in WAN. The system display center runs normally and the data transmission is stable. The scheme has the characteristics of long communication distance, simple deployment and low cost, and adheres to the concept of green ecological aquaculture, which can provide an effective reference for the application of aquaculture and Internet of Things.