To explore the responses of Sebastes schlegelii to different dissolved oxygen environments,We selected juvenile S. schlegelii with an average weight of (0. 520 ± 0. 130 g) and set up 4 groups of different DO ( 3,5,7, 10 mg/L). The experimental period was 28 days, and the effects of different dissolved oxygen levels on the movement behavior, growth performance,and blood biochemistry of juvenile S. schlegelii were observed and analyzed. The results showed that : with the increase of dissolved oxygen levels,the spontaneous swimming speed,inter-individual distance and nearest neighbor distance of the experimental fish significantly increased and reached the highest in group 10 mg/L,while cohesion,coordination and polarity gradually decreased. With the increase of dissolved oxygen levels,the survival rate,specific growth rate,feed conversion rate ,liver-to-body ratio and viscera-to-body ratio of the experimental fish significantly increased and reached the maximum in Group 10 mg/L. With the increase of dissolved oxygen levels,the contents of total protein,total cholesterol and triglyceride in the blood of the fish gradually increased,the contents of glucose and alanine aminotransferase first decreased and then remained stable,the content of aspartate aminotransferase first decreased and then increased.