To study the high-density recirculating aquaculture model after feeding, the dissolved oxygen level drops sharply, causing the floating head of fish to lose oxygen and other problems. Taking red tilapia as an example, a closed hydrostatic experiment method was adopted, and the system was stopped during feeding. Circulate and measure the oxygen consumption of the fish in the whole pond. By controlling the temperature (26°C, 29°C, 32°C) and feeding rate (0.4%, 0.6%, 0.8%, 1.0%, 1.2%), the oxygen consumption of red tilapia before feeding, feeding oxygen consumption, and the change in the oxygen consumption 2 hours after feeding were observed. Changes in oxygen consumption were investigated by two-way ANOVA. The results showed that temperature and feeding rate had significant interaction effects on oxygen consumption of red tilapia. In the temperature range of 26-32℃, with the increase in temperature, the oxygen consumption before feeding also increased, and the difference was extremely significant (P<0.001). The linear regression equation of oxygen consumption before feeding and temperature is: y = 0.961 7 x -14.125 (R² = 0.9903). The oxygen consumption of food increased with the increase in feeding amount, and the oxygen consumption of red tilapia 2 h after feeding also followed this law. Studies have shown that the oxygen consumption of red tilapia has a linear relationship with temperature before feeding, but not after feeding. The more red tilapia feeding the feed, the slower the metabolic recovery speed of fish after feeding under a certain range of feeding rate.