In order to effectively solve the problems of lack of variety for cages in North China and to reasonably utilize idle cages,  the land-sea relay aquaculture experiments in a land-sea relay model of Oncorhynchus mykiss were carried out to compare with industrialized aquaculture, thus the survival rate of Oncorhynchus mykiss can be improved, and economic efficiency can be increased. Results showed that: The initial body weights of the three species of Oncorhynchus mykiss were (225.1 ± 36.2)g, (102.8 ± 23.5)g and (55.3 ± 12.3)g; the average weights reached( 2 143.4 ± 253.1)g, (1 763.8± 210.3)g and (946.3 ± 120.4)g, and the survival rates reached 91.2%, 90.6%, 89.3% after 384 days of industrialized aquaculture; the average weights reached (2 408.3 ± 321.2)g, (2 065.5 ± 256.3)g and (1 142.6 ± 156.3)g, and the survival rates reached( 87.5% %, 88.1% and 85.3%, of which the average daily body weight of large-size seedlings reached 8.5g/d after 384 days of land-sea relay aquaculture. Thus it can be seen the most suitable size of Oncorhynchus mykiss for land-sea relay aquaculture was the medium size with a more than 100g of weigh; the land-sea relay aquaculture, with fast growth, high economic benefit, is a new aquaculture pattern for the aquaculture of Oncorhynchus mykiss that is worthy to be popularized.