In order to improve the survival time and survival rate of Macrobrachium rosenbergii, the optimum condition of zeolite modification process was determined by orthogonal experiment through microwave and ultrasonic strengthening of Nacl solution, and the effects of ammonia nitrogen concentration and pH, zeolite dosage and adsorption time on the adsorption performance were tested. The changes of survival rate and water quality index during the keep-alive process were studied, and the characterization of modified zeolite was analyzed. The results showed that zeolites with particle size of 1～2mm were modified through microwave (230W, 10min) and ultrasonic (560W, 28kHz, 50min) strengthening of NaCl solution (morality of 0.8 mol/L). The removal rate of ammonia nitrogen by adding 30g/L modified zeolite for one hour of adsorption into water with ammonia nitrogen concentration of 20mg/L and pH of 7.00 was 20.88% higher than that of unmodified zeolite. The characterization showed that the specific surface area of the modified zeolites increased without damaging the crystal lattice, the exchange rate of Na+ significantly increased and the ratio of Si to Al increased, which could well maintain the charge balance. The survival rate of Macrobrachium rosenbergii was significantly improved and its water quality index was effectively controlled. Therefore, the modified zeolite through microwave - ultrasonic strengthening of Nacl solution can effectively remove ammonia nitrogen to prolong the survival time and improve the survival rate of Macrobrachium rosenbergii.