In order to keep the artificial reefs stable on the silty substrate without sedimentation, a new type of artificial reefs is proposed in this paper, mainly including the reef body, buoyancy foundation, and cylindrical piles. Based on the surveyed and measured geological, hydrological, extreme wind and wave flow, Stockes wave theory and Fluent software were used to simulate the flow field effects around the reefs, and the environmental loads on the artificial reefs were calculated through theoretical analysis and numerical simulation. Through theoretical analysis, the pull-out resistance and horizontal resistance of the negative-pressure cylindrical pile under the silt foundation were obtained. Finally, it was obtained that the new artificial reefs can be kept stable without sedimentation under a given release environment, and its anti-slip and anti-overturning safety factors under the action of wave current can meet the specifications. This study provides a method for the design of artificial reefs on silty substrates, and has certain guiding significance.