Biofloc technology has the advantages of purifying water quality and improving the utilization rate of feed protein, survival rate and disease resistance. In order to analyze the development trend of this technology, PatSnap platform and bibliometric method were used to analyze the overall situation of patents, application trends, patent technology composition, distribution of innovative subjects, special patents and patent values. The results showed that the technology had grown rapidly, and the main patent type was patent for invention. Some patents had higher quality and valuation. The main compositions were A01K (animal husbandry; care of birds, fishes, insects; fishing; rearing or breeding animals, not otherwise provided for; new breeds of animals), C02F (treatment of water, waste water, sewage, or sludge), C12N (microorganisms or enzymes; compositions thereof) and A23K (feeding-stuffs specially adapted for animals; methods specially adapted for production thereof). The research focused on the cultivation of shrimps and fishes, biofloc feed and recirculating aquaculture, etc. Enterprises and scientific research institutions were the main patent applicants, where the innovation ability of scientific research institutions was stronger. The patent advantage in coastal areas was obvious, and the province with the most patented technology distribution was Guangdong province. In order to break through the shortcomings of biofloc technology, it is recommended to pay attention to the role of patent analysis of such technology in the future, and industry-university-research as well as regional level cooperation should be strengthened. Thus, the marketization and industrialization of this technology could be promoted.