In order to effectively regulate the water condition in high density mariculture ponds, a recirculating mariculture system for “fish, shrimp, shellfish and plant” was built with constructed wetland as the core. The operation mode and plant species in the constructed wetland that are compatible with the mariculture system were studied by comparing the purification efficiency of continuous flow and intermittent flow and the efficiency when Salicornia europaea and Spatina alterniflora are planted. By comparing the pond water quality and the growth rate of the cultured species under different culture mode, the regulation effects of constructed wetland on the pond water quality were analyzed, and the effects of the recirculating mode on promoting the yield were evaluated. Results show that the purification efficiency of the constructed wetland was significantly higher in intermittent operation (the hydraulic load was 300mm/d.) compared to that in continuous operation. The nitrogen and phosphorus concentrations in the effluent of constructed wetland with Salicornia europaea was significantly lower than that that with Spatina alterniflora. The NH4+-N and NO2--N concentrations in the pond water under the recirculating mode and under the traditional mode were both at a low level, though the frequencies of water discharge and exchange were different. The polyculture of Meretrix meretrix and Exopalaemon carinicauda in different ponds based on wetland circulating water treatment can further improve the yield per unit area of Exopalaemon carinicauda and effectively control the discharge of aquaculture wastewater. The study shows that the recirculating mariculture system based on constructed wetland has strong environmental benefits, and can provide reference for healthy development of mariculture in Jiangsu Province.